3M DuraPrep Surgical Prepping Solution gives you effective antimicrobial kill in a single, painted coat, along with significantly greater drape adhesion when compared to ChloraPrep Antiseptic.1 3M DuraPrep Surgical Prepping Solution, is not povidone iodine and is not represented in any clinical study that references PVP-I. 3M DuraPrep Surgical Prepping Solution keeps resident bacterial counts low for at least 48 hours after blood and saline challenge, and at least 12 hours against transient bacteria. Don't let the applicators fool your surgical team. Only one surgical patient prep is NDA approved by the FDA to be applied in a single, painted, coat with no scrubbing: 3M DuraPrep Surgical Prepping Solution.